Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...

Nightmares and Night Terrors

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...

Sleep-Wake Cycles

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:

Dementia

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....

Dementia l: Introduction

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

Insufficient Sleep and Sleep Deprivation

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Survey on awareness of sleep medicine among members of the Japanese Society of Neurology.

Rinsho shinkeigaku = Clinical neurology·2026

Same author

Designing Infant Mattresses Tailored to Developmental Sleep Characteristics: A Comprehensive Review.

Clocks & sleep·2025

Same author

Development and field test of the child and adolescent sleep checklist for parents of community junior high school students.

Frontiers in child and adolescent psychiatry·2025

Same author

Daridorexant in Japanese patients with insomnia disorder: A phase 3, randomized, double-blind, placebo-controlled study.

Sleep medicine·2024

Same author

Referrals of pediatric patients to a sleep center during its first 5 years.

Sleep and biological rhythms·2024

Same author

The Japanese version of the children's sleep habits questionnaire (CSHQ-J): A validation study and influencing factors.

Brain & development·2022

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

[Sleep problems in dementia].

¹Center for Sleep Medicine, Ehime University Hospital.

Rinsho Shinkeigaku = Clinical Neurology

|February 13, 2015

Summary

Sleep disturbances are frequent in dementia patients due to disrupted sleep-wake cycles. Addressing these sleep issues, including circadian rhythm disorders, can improve dementia management.

Area of Science:

Neurology
Sleep Medicine
Gerontology

Background:

Sleep disturbances are highly prevalent in individuals with dementia.
These issues stem from disrupted central nervous system sleep-wake regulation, sensory input alterations, and reduced social engagement.

Purpose of the Study:

To explore the relationship between sleep disturbances and dementia.
To outline effective therapeutic strategies for managing sleep disorders in dementia patients.

Main Methods:

Analysis of circadian rhythm abnormalities in dementia.
Review of age-related sleep changes and neurodegeneration-induced sleep disorders (e.g., REM sleep behavior disorder).

Main Results:

Alzheimer's disease patients exhibit reduced amplitude and shifted peaks in diurnal serum melatonin levels.

More Related Videos

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

Related Experiment Videos

Last Updated: Apr 17, 2026

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

Age-related sleep disturbances and neurodegeneration-associated sleep disorders are more common in dementia.

Conclusions:

Identifying and treating underlying sleep disorders is crucial for dementia care.
Therapeutic approaches targeting circadian mechanisms, including light therapy, increased daytime activity, and oral melatonin, can improve nocturnal sleep and aid overall dementia management.