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Ultrasound-guided core biopsy.
P E Jennings1, J J Donald, A Coral
1Department of Diagnostic Imaging, Middlesex Hospital, London.
Lancet (London, England)
|June 17, 1989
Summary
Ultrasound-guided core needle biopsies are a safe and effective method for diagnosing malignancy, achieving high accuracy and a low complication rate. This technique provides reliable histological specimens for definitive diagnosis.
Area of Science:
- Medical Imaging
- Pathology
- Surgical Oncology
Background:
- Accurate histological diagnosis is crucial for effective cancer management.
- Minimally invasive biopsy techniques are preferred to reduce patient risk and improve diagnostic yield.
- Ultrasound guidance enhances precision in tissue sampling.
Purpose of the Study:
- To evaluate the efficacy and safety of ultrasound-guided core needle biopsy for diagnosing malignancy.
- To determine the sensitivity, accuracy, and complication rates associated with this biopsy technique.
Main Methods:
- A retrospective review of 404 ultrasound-guided core needle biopsies performed between February 1986 and September 1988.
- Utilized a spring-loaded device for rapid cutting needle deployment.
- Assessed diagnostic accuracy, sensitivity, positive predictive value, and complication rates.
Main Results:
- Achieved a sensitivity of 92.7% for malignancy diagnosis.
- Reported an overall accuracy of 94.1%.
- Demonstrated a 100% positive predictive value and a low complication rate. Histological examination yielded an exact diagnosis in 98% of positive tumor biopsies.
Conclusions:
- Ultrasound-guided core needle biopsy is a simple, safe, and highly accurate method for obtaining tissue for histological diagnosis.
- The technique offers excellent sensitivity and a low complication rate, making it a valuable tool in cancer diagnosis.