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The role of factor Xa inhibitors in venous thromboembolism treatment

Katherine P Cabral1, Jack E Ansell2

  • 1Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, NY, USA.

Vascular Health and Risk Management
|February 13, 2015
PubMed

Three factor Xa inhibitors have been studied in the treatment of venous thromboembolism, both for acute therapy and as extended therapy to prevent recurrent events. Rivaroxaban, apixaban, and edoxaban have all proven to be effective in Phase III clinical trials for this indication when compared to current standard of therapy with similar or less bleeding. Nevertheless, the agents all offer different pharmacological profiles, which have an impact on patient selection and potential advantages in clinical practice.

Keywords:
anti-Xa inhibitorsapixabanedoxabanrivaroxabanvenous thromboembolism

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