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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

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Association between arterial stiffness and risk of coronary artery disease

Ke-Qin Luo1, Xiao-Wei Feng2, Bing-Can Xu3

  • 1Ke-qin Luo, Department of Emergency, SunYat-Sen memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.

Pakistan Journal of Medical Sciences
|February 13, 2015
PubMed

Insights

Brachial ankle Pulse Wave Velocity (baPWV) and carotid-femoral PWV (cfPWV) are independent risk factors for Coronary Artery Disease (CAD). Both baPWV and cfPWV interact with age and lipid profiles, highlighting their importance in CAD risk assessment.

Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Epidemiology

Background:

  • Pulse wave velocity (PWV) measures arterial stiffness, a key indicator of cardiovascular health.
  • Brachial ankle (baPWV) and carotid-femoral (cfPWV) are established methods for assessing PWV.
  • Arterial stiffness is increasingly recognized as a significant risk factor for Coronary Artery Disease (CAD).

Purpose of the Study:

  • To evaluate the independent and interactive roles of baPWV and cfPWV in predicting CAD risk.
  • To investigate the interplay between baPWV, cfPWV, and traditional CAD risk factors.

Main Methods:

  • A case-control study involving 332 CAD patients and 328 controls.
  • Data collected between February 2012 and October 2013.
  • Multivariate logistic regression analysis employed to identify risk factors and interactions.

Main Results:

  • CAD patients exhibited higher baPWV and cfPWV compared to controls.
  • Older age, hypertension, dyslipidemia (TC, TG, HDL-C, LDL-C), smoking, and elevated PWV were associated with increased CAD risk.
  • Significant interactions were observed between baPWV and age, TC, TG, HDL-C, and LDL-C; cfPWV interacted with age, HDL-C, and LDL-C.

Conclusions:

  • baPWV and cfPWV are independent predictors of CAD.
  • The predictive value of baPWV and cfPWV in CAD risk is modulated by age and lipid profiles.
  • These findings underscore the clinical utility of PWV measurements in comprehensive cardiovascular risk assessment.
Abstract

Keywords:
Arterial stiffnessCoronary Artery DiseasebaPWVcfPWV

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