[In memoriam. Remembering Alicia Llacer (1947-2014)]

Repressed memories are a psychological phenomenon where memories of traumatic events are unconsciously blocked from a person's awareness. This process occurs as a defense mechanism, protecting the mind from the emotional impact of distressing or painful experiences. For example, a person who has experienced childhood trauma may grow up with no conscious recollection of the event. In such cases, the memories are thought to be buried deep within the subconscious, inaccessible to the conscious...

Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...

A flashbulb memory is a highly vivid and detailed memory, often linked to events of significant emotional impact. These memories stand out in contrast to everyday memories due to their clarity and the precision with which they are recalled. The strong emotions associated with the event act as a catalyst, ensuring that specific details, such as one's location, actions, and even peripheral elements, are etched into memory with remarkable accuracy. For example, many people can vividly recall...

Autobiographical memory is a unique type of episodic memory that involves recollecting personal life experiences. It allows individuals to remember significant events from their past, creating a narrative of their lives. One interesting phenomenon related to autobiographical memory is the reminiscence bump. This effect refers to the tendency of adults to recall more events from their second and third decades of life — typically between ages 10 to 30 — than from other periods. This...

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...