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Published on: August 9, 2024
Choristomatous Respiratory Cyst Restricted to the Upper Eyelid
Frederick A Jakobiec1, Miin Roh, Anna M Stagner
1*Department of Ophthalmology, †David G. Cogan Laboratory of Ophthalmic Pathology, and ‡Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, U.S.A.
Abstract:
A 79-year-old man underwent excision of an upper eyelid mass that had been enlarging for 3 months. Histopathologic evaluation demonstrated a cyst lined by pseudostratified columnar epithelium with myriad goblet cells and cilia, and immunostaining revealed cytokeratins indicative of a respiratory origin. This rare condition, the first described exclusively in an eyelid, arises either from a congenital embryologic respiratory epithelial ectopia or the displacement of mature sinus mucosa following trauma or chronic sinus disease. The current case lacked any signs or symptoms of sinus disease or a history of trauma.
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