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The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
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Innate hypothermia after hypoxic ischaemic delivery

Dulip Jayasinghe1

  • 1Nottingham Neonatal Service, Nottingham University Hospitals NHS Trust, Nottingham, UK.

Neonatology
|February 14, 2015
PubMed

The focus of this review is to collate the literature on the phenomenon of impaired thermal adaptation after hypoxic ischaemic (HI) delivery often culminating in hypothermia. This phenomenon appears different in severity and duration to a spontaneous postnatal fall in temperature observed after normal delivery. The original observation and contemporary descriptions of the temperature response to HI are described and a mechanism of action is proposed that may be utilised as a novel biomarker for HI.

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