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Updated: May 3, 2026

Generation of High Quality Chromatin Immunoprecipitation DNA Template for High-throughput Sequencing ChIP-seq
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A susceptibility locus for multiple sclerosis is linked to the T cell receptor beta chain complex

E Seboun1, M A Robinson, T H Doolittle

  • 1Neuroimmunology Unit, Massachusetts General Hospital, Boston 02114.

Cell
|June 30, 1989
PubMed
Summary

Genetic analysis of T cell receptor beta (TCR beta) genes in multiple sclerosis (MS) families revealed a significant link. Specific TCR beta gene segments are overrepresented in individuals with MS, suggesting a genetic susceptibility.

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