Related Experiment Video
Updated: Apr 17, 2026
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Determination of sex: interest of frontal sinus 3D reconstructions
Justin Michel1, Arnaud Paganelli, Arthur Varoquaux
1Department of Oto-Rhino-Laryngology - Head and Neck Surgery, University Hospital La Timone, 264 rue St. Pierre, 13385 Cedex 5, Marseille, France; Unité d'Anthropologie Bioculturelle, CNRS-EFS, Faculté de Médecine Nord, UMR 6578, Aix-Marseille Université, 51 Boulevard Pierre Dramard, 13916, Marseille, France.
Abstract:
Frontal sinuses (FSs) have been studied in radiology, anthropology, and forensic anthropology. This study aimed to determine whether it was possible to predict the age and sex of an individual using FS volume. Sixty-nine anonymized CT scans were imported to MIMICS 10.01(®) software (Materialise N.V.), and each FS volume was calculated in mm(3) . There was an absence of significant difference between right and left FS volume (p = 0.173) and an absence of correlation between age and FS volume (Pearson's test; p = 0.705). Sexual dimorphism was significantly different (p = 0.001). However, the most discriminant datum for determining sex was found to be the total FS volume (sum of an individual's right and left FS volumes) with linear discriminant Fisher's function coefficients of -2.759 for the male group and -1.275 for the female group. With this model, 72.5% of our sample was correctly classified according to sex.
