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Related Experiment Video

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The Measurement and Treatment of Suppression in Amblyopia
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Published on: December 14, 2012

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Dichoptic training improves contrast sensitivity in adults with amblyopia.

Jinrong Li1, Daniel P Spiegel2, Robert F Hess3

  • 1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Vision Research
|February 14, 2015
PubMed
Summary

Dichoptic training significantly improved contrast sensitivity (CS) in adults with amblyopia. These findings suggest that this visual therapy enhances neural systems underlying monocular vision.

Keywords:
AmblyopiaBinocular visionContrast sensitivityDichoptic trainingPerceptual learning

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Vision Science

Background:

  • Amblyopia, or

Purpose of the Study:

  • To investigate if dichoptic training enhances contrast sensitivity (CS) in adults with amblyopia.
  • To determine if improvements in CS transfer to monocular visual functions after dichoptic training.

Main Methods:

  • Analyzed contrast sensitivity (CS) data from 30 adults with amblyopia who underwent 10-day dichoptic training.
  • Measured CS using Gabor patches at 0.5, 3, and 10cpd before and after training.
  • Training involved dichoptic video games on video goggles or iPod touch (with or without tDCS).

Main Results:

  • Dichoptic training significantly improved CS across all tested spatial frequencies.
  • Improvements in CS were observed in both training groups.
  • The observed changes in CS exceeded test-retest variability.

Conclusions:

  • Dichoptic training is effective in improving contrast sensitivity (CS) in adults with amblyopia.
  • The training appears to modify the neural systems responsible for monocular CS.
  • These findings support dichoptic training as a therapeutic approach for visual function enhancement in amblyopia.