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Updated: Apr 17, 2026
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry
Gilda Cennamo1, Elisabetta Chiariello Vecchio1, Marialuisa Finelli1
1Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy.
Objective:
To evaluate the efficacy of high-speed Fourier-domain optical coherence tomography (FD-OCT) and fundus microperimetry (MP-1) in identifying the anatomic and functional features of ischemic diabetic maculopathy.
Design:
Prospective noninterventional study.
Participants:
Forty-two consecutive eyes (23 patients) with ischemic diabetic maculopathy and 40 normal eyes (25 control subjects) were included in this study.
Methods:
Best corrected visual acuity, ganglion cell complex (GCC) thickness measured with FD-OCT, and central light sensitivity recorded with MP-1 were evaluated.
Results:
GCC thickness and light sensitivity were significantly reduced in all affected eyes versus control eyes. logMAR BVCA was significantly correlated with mean macular sensitivity (R=0.783, R(2)=0.611).
Conclusions:
GCC thickness and microperimetry integrated with fluorescein angiography could be a marker of retinal vascular abnormalities that is useful for the diagnosis of ischemic diabetic maculopathy.
