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Updated: Apr 17, 2026

Measurements of Physiological Stress Responses in C. Elegans
Published on: May 21, 2020
Bacterial histone-like proteins: roles in stress resistance
1Department of Microbiology, University of Georgia, 815 Biological Sciences Building, Athens, GA, 30602, USA.
Abstract:
Histone-like proteins (HLPs) are small and basic bacterial proteins that are associated with a nucleoid and play roles in maintaining DNA architecture and regulating DNA transactions such as replication, recombination/repair and transcription. The studies on HLPs from a variety of bacterial species in recent years are summarized in this mini-review. A recent study reported a novel DNA-binding protein (HP119) in Helicobacter pylori that shows some HLP features. It plays a large role in aiding bacterial stress resistance. We provide herein additional evidence that HP119 is a nucleoid-associated protein, and present some perspectives for future study.
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