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Updated: Apr 17, 2026
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Behçet's disease and comorbidity: internal case reports and literature review
Zemfira Alekberova1, Vadim Gorodetskiy1, Fatima Izmailova2
1Nasonova Research Institute of Rheumatology, Moscow, Russia.
Insights
Malignancy is a rare complication of Behçet
Area of Science:
- Rheumatology
- Oncology
- Hematology
Background:
- Behçet's disease is a rare multisystemic inflammatory disorder.
- Malignant transformation in Behçet's disease is infrequently reported.
- Associations include myelodysplastic syndrome, neoplasms, and leukemia.
Abstract:
The aim of this study was to determine the clinical characteristics of two patients with malignancy related to Behçet's disease. We reviewed literary-reported cases of Behçet's disease related to myelodysplastic syndrome, neoplasm and leukemia. Our own observation included two cases of comorbid conditions of Behçet's disease. The first patient with Behçet's disease had been examined concurrent development of intestinal tumor. The second one was diagnosed to have chromic myeloleukemia. The malignant transformation of Behçet's disease patients, both solid and hematological, is rather rare. Further accumulation of relevant date and its analysis will allow to find out the relationship between malignant disease and chemotherapy in Behçet's disease.
