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Differences in clinical features and outcomes between group A and group G Streptococcus -induced cellulitis
Yurie Komatsu1, Aki Okazaki, Kazuhisa Hirahara
1Department of Dermatology, Kyorin University School of Medicine, Mitaka, Japan.
Dermatology (Basel, Switzerland)
|February 14, 2015
Summary
Group G Streptococcus (GGS) cellulitis presents variably in older adults with underlying conditions, unlike the uniform presentation of Group A Streptococcus (GAS) cellulitis. Identifying predisposing factors aids in predicting GGS cellulitis outcomes.
Area of Science:
- Infectious Diseases
- Bacteriology
- Dermatology
Background:
- Streptococci are primary causes of cellulitis.
- Group G Streptococcus (GGS) shares virulence factors with Group A Streptococcus (GAS).
- Clinical distinctions between GAS- and GGS-induced cellulitis are not well-defined.
Purpose of the Study:
- To differentiate clinical manifestations and outcomes of lower limb cellulitis caused by GAS versus GGS.
- To characterize the clinical presentation variability of GGS cellulitis.
- To identify predictors for GGS cellulitis course and prognosis.
Main Methods:
- Retrospective analysis of 29 patients with lower limb cellulitis.
- Inclusion criteria: diagnosis of GAS or GGS lower limb cellulitis.
- Study period: January 2008 to September 2013.
Main Results:
- GAS cellulitis showed uniform clinical features.
- GGS cellulitis exhibited variable manifestations, influenced by predisposing factors.
- GGS cellulitis was more prevalent in older individuals with chronic illnesses.
Conclusions:
- Clinical predisposing factors can predict the course and outcomes of GGS-induced cellulitis.
- Understanding these factors is crucial for managing GGS cellulitis effectively.
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