Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

14.9K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
14.9K
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

22.2K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
22.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Airborne Ultrasound Surface Motion Camera: Application to Transfer Admittance Chest Imaging.

Annals of biomedical engineering·2026
Same author

Streamlined optical training of large-scale modern deep learning architectures with direct feedback alignment.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Hydrogel metapad with ultrasound transparency and broadband focusing for biomedical imaging.

National science review·2026
Same author

Two-photon microscopy through scattering media harnessing speckle autocorrelation.

Optics express·2025
Same author

Three-dimensional holographic imaging of incoherent objects through scattering media.

Nature communications·2025
Same author

Matrix-based imaging through dynamic scattering.

Nature communications·2025

Related Experiment Video

Updated: Apr 17, 2026

Lensless Fluorescent Microscopy on a Chip
11:23

Lensless Fluorescent Microscopy on a Chip

Published on: August 17, 2011

18.4K

Scanning-free imaging through a single fiber by random spatio-spectral encoding.

Sylwia M Kolenderska, Ori Katz, Mathias Fink

    Optics Letters
    |February 14, 2015
    PubMed
    Summary

    This study introduces a novel 2D imaging method using a single fiber and a scattering medium. This technique eliminates the need for scanners and is robust against fiber bending, ideal for endoscopy.

    More Related Videos

    Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis
    10:57

    Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis

    Published on: February 1, 2022

    3.7K
    Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
    08:48

    Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

    Published on: September 5, 2012

    12.5K

    Related Experiment Videos

    Last Updated: Apr 17, 2026

    Lensless Fluorescent Microscopy on a Chip
    11:23

    Lensless Fluorescent Microscopy on a Chip

    Published on: August 17, 2011

    18.4K
    Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis
    10:57

    Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis

    Published on: February 1, 2022

    3.7K
    Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution
    08:48

    Optical Recording of Suprathreshold Neural Activity with Single-cell and Single-spike Resolution

    Published on: September 5, 2012

    12.5K

    Area of Science:

    • Optics and Photonics
    • Biomedical Imaging
    • Materials Science

    Background:

    • Traditional 2D imaging often requires bulky scanning mechanisms.
    • Fiber-based imaging is desirable for minimally invasive procedures but faces challenges with signal encoding and robustness.
    • Scattering media can manipulate light, but their application in direct imaging through single fibers is complex.

    Purpose of the Study:

    • To develop a scanner-free 2D imaging approach utilizing a single optical fiber.
    • To encode spatial information from a 2D object into spectral signatures using a scattering medium.
    • To demonstrate the feasibility of reconstructing 2D images from spectral data collected at the fiber's proximal end.

    Main Methods:

    • A random scattering medium was integrated at the fiber's distal end.
    • Each pixel of the 2D object was encoded with a unique random spectral signature via scattering.
    • 2D images were reconstructed from a single spectral measurement at the fiber's proximal end.
    • The system's performance was evaluated with externally illuminated 2D objects.

    Main Results:

    • Successful 2D imaging of externally illuminated objects was demonstrated through a single fiber.
    • The technique successfully encoded spatial information into distinct spectral signatures.
    • The imaging approach proved insensitive to fiber bending, a critical factor for endoscopic use.
    • A single spectrum measurement at the fiber's proximal end was sufficient for image reconstruction.

    Conclusions:

    • The proposed method offers a novel, scanner-free approach for 2D imaging via a single fiber.
    • The use of a scattering medium for spectral encoding provides a robust and potentially cost-effective imaging solution.
    • The insensitivity to fiber bending highlights its potential for advanced endoscopic imaging applications.