Related Experiment Video
Updated: Apr 17, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
Psychotherapy use in bipolar disorder: Association with functioning and illness severity
Louisa G Sylvia1, Michael E Thase2, Noreen A Reilly-Harrington3
1Massachusetts General Hospital, Boston, USA Harvard Medical School, Boston, USA lsylvia2@mgh.harvard.edu.
Only 31% of bipolar disorder patients use psychotherapy. Those who do report higher illness burden, including medication side effects, anxiety, and suicide risk, indicating a need for integrated care.
Area of Science:
- Psychiatry
- Clinical Psychology
- Mental Health Services Research
Background:
- Bipolar disorder is a chronic mental health condition requiring comprehensive treatment.
- Psychotherapy is a key component of managing bipolar disorder, alongside pharmacotherapy.
- Understanding patient characteristics associated with psychotherapy use is crucial for optimizing care.
Purpose of the Study:
- To compare demographic and clinical characteristics of bipolar disorder patients who use psychotherapy versus those who do not.
- To investigate treatment response and time to recovery based on psychotherapy utilization.
Main Methods:
- Analysis of data from the 11-site Bipolar CHOICE study (N=482).
- Baseline assessments included psychotherapy use, mood, functioning, and health.
- Logistic regression, mixed-effects regression, Kaplan-Meier plots, and log-rank tests were used.
Main Results:
- 31% of participants utilized psychotherapy services.
- Psychotherapy users had greater medication side effect burden, higher suicide risk, and more anxiety disorders.
- Non-medication/non-psychotherapy users had greater mania severity, were younger, and less educated.
Conclusions:
- A minority of individuals with bipolar disorder engage in psychotherapy.
- Patients seeking psychotherapy exhibit a greater overall illness burden.
- Findings highlight the need for better integration of psychotherapy in bipolar disorder treatment.
More Related Videos
12:19Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression
Published on: April 10, 2026
09:55Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Related Concept Videos
Bipolar Disorder
Psychosis: Goals of Pharmacotherapy
Mania and Antimanic Drugs: Overview
Psychosis and Antipsychotic Drugs: Overview
Drug Therapy
Antianxiety Medications
Interpersonal Psychotherapy