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Published on: March 14, 2025
[DRESS syndrome induced by ciprofloxacine]
Rym Sahnoun1, Sihem El Aïdli1, Ahmed Zaïem1
1Centre national de pharmacovigilance de Tunis, 9, avenue du Dr Zouheir Essafi, 1006 Bab Souika Tunis, Tunisie; Faculté de médecine de Tunis, université Tunis El Manar, 15, rue Djebel Lakhdhar, La Rabta, 1007 Tunis, Tunisie.
Abstract:
The Drug rash with hypereosinophilia and systemic symptoms (DRESS) syndrome, or hypersensitivity syndrome, is a severe drug-induced hypersensitivity syndrome. It has been exceptionally described with ciprofloxacin. We report a 47-year-old-woman who developed DRESS syndrome, 2 days after taking ciprofloxacin for a urinary infection. She had a generalized maculopapular rash, severe rhabdomyolysis, liver involvement, renal failure and hypereosinophilia. Clinical symptoms had completely resolved after ciprofloxacin withdrawal. Renal failure has decrease after short corticosteroid treatment.
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