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Updated: Apr 17, 2026

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model
Published on: October 2, 2020
An advanced image analysis tool for the quantification and characterization of breast cancer in microscopy images
Theodosios Goudas1, Ilias Maglogiannis
1Department of Digital Systems, University of Piraeus, Grigoriou Lampraki 126, PC 18532, Piraeus, Greece, goudas@unipi.gr.
Abstract:
The paper presents an advanced image analysis tool for the accurate and fast characterization and quantification of cancer and apoptotic cells in microscopy images. The proposed tool utilizes adaptive thresholding and a Support Vector Machines classifier. The segmentation results are enhanced through a Majority Voting and a Watershed technique, while an object labeling algorithm has been developed for the fast and accurate validation of the recognized cells. Expert pathologists evaluated the tool and the reported results are satisfying and reproducible.

