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Updated: Apr 17, 2026
Controlled Synthesis and Fluorescence Tracking of Highly Uniform PolyN-isopropylacrylamide Microgels
Published on: September 8, 2016
Templateless synthesis of polyacrylamide-based Nanogels via RAFT dispersion polymerization
Kai Ma1, Yuanyuan Xu, Zesheng An
1Institute of Nanochemistry and Nanobiology, College of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, China; Department of Chemistry, Shanghai University, Shanghai, 200444, China.
Abstract:
This paper reports on the synthesis of well-defined polyacrylamide-based nanogels via reversible addition-fragmentation chain transfer (RAFT) dispersion polymerization, highlighting a templateless route for the efficient synthesis of nanogels based on water-soluble polymers. RAFT dispersion polymerization of acrylamide in co-nonsolvents of water-tert-butanol mixtures by chain extension from poly(dimethylacrylamide) shows well-controlled polymerization process, uniform nanogel size, and excellent colloidal stability. The versatility of this approach is further demonstrated by introducing a hydrophobic co-monomer (butyl acrylate) without disturbing the dispersion polymerization process.
