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Updated: Apr 17, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
From the History of Science to the History of Knowledge - and Back
Abstract:
The history of science can be better understood against the background of a history of knowledge comprising not only theoretical but also intuitive and practical knowledge. This widening of scope necessitates a more concise definition of the concept of knowledge, relating its cognitive to its material and social dimensions. The history of knowledge comprises the history of institutions in which knowledge is produced and transmitted. This is an essential but hitherto neglected aspect of cultural evolution. Taking this aspect into account one is led to the concept of extended evolution, which integrates the perspectives of niche construction and complex regulative networks. The paper illustrates this concept using four examples: the emergence of language, the Neolithic revolution, the invention of writing and the origin of mechanics.
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