Correlation between changes in diastolic dysfunction and health-related quality of life after cardiac rehabilitation
1Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Insights
Cardiac rehabilitation programs improve heart function and quality of life in patients with chronic heart failure. Exercise training specifically enhanced diastolic function, correlating with better health-related quality of life.
Area of Science:
- Cardiology
- Exercise Physiology
Background:
- Chronic heart failure (CHF) involves progressive left ventricular dysfunction, impacting exercise tolerance, mortality, and morbidity.
- Left ventricular diastolic dysfunction is a key factor in CHF progression and various cardiac conditions.
Purpose of the Study:
- To assess the impact of a cardiac rehabilitation program on diastolic dysfunction and health-related quality of life (HRQoL) in CHF patients.
- To investigate the correlation between improvements in left ventricular diastolic dysfunction and HRQoL domains.
Main Methods:
- Forty patients with dilated cardiomyopathy (DCM) and systolic/diastolic dysfunction were randomized into training and control groups.
- The training group underwent a 7-month circuit-interval aerobic training program (55-80% heart rate reserve).
- Thirty patients completed the study; outcomes were assessed using the Kansas City Cardiomyopathy Questionnaire.
Main Results:
- Circuit training significantly improved both diastolic and systolic dysfunction in the training group.
- A significant correlation was observed between enhanced diastolic function and improved HRQoL.
- No significant changes were noted in the control group.
Conclusions:
- Cardiac rehabilitation, particularly aerobic exercise, effectively improves diastolic dysfunction in DCM patients.
- Improvements in diastolic function are a crucial mechanism underlying enhanced HRQoL following rehabilitation.
- Rehabilitation programs offer a viable strategy for managing diastolic dysfunction and improving patient well-being in CHF.
Abstract:
Chronic heart failure (CHF) is a complex syndrome characterized by progressive decline in left ventricular function, low exercise tolerance and raised mortality and morbidity. Left ventricular diastolic dysfunction plays a major role in CHF and progression of most cardiac diseases. The current recommended goals can theoretically be accomplished via exercise and pharmacological therapy so the aim of the present study was to evaluate the impact of cardiac rehabilitation program on diastolic dysfunction and health related quality of life and to determine the correlation between changes in left ventricular diastolic dysfunction and domains of health-related quality of life (HRQoL). Forty patients with chronic heart failure were diagnosed as having dilated cardiomyopathy (DCM) with systolic and diastolic dysfunction. The patients were equally and randomly divided into training and control groups. Only 30 of them completed the study duration. The training group participated in rehabilitation program in the form of circuit-interval aerobic training adjusted according to 55-80% of heart rate reserve for a period of 7 months. Circuit training improved both diastolic and systolic dysfunction in the training group. On the other hand, only a significant correlation was found between improvement in diastolic dysfunction and health related quality of life measured by Kansas City Cardiomyopathy Questionnaire. It was concluded that improvement in diastolic dysfunction as a result of rehabilitation program is one of the important underlying mechanisms responsible for improvement in health-related quality of life in DCM patients.
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