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Updated: Apr 17, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A
Mohamed-Elamir F Hegazy1, Tarik A Mohamed2, Abdelsamed I ElShamy3
1Phytochemistry Department and Center of Excellence for Advanced Sciences, National Research Centre, El-Tahrir Street, Dokki, Giza 12622, Egypt ; Phytochemistry Department, National Research Centre, El-Tahrir Street, Dokki, Giza 12622, Egypt.
Abstract:
Natural products are structurally and biologically interesting metabolites, but they have been isolated in minute amounts. The syntheses of such natural products help in obtaining them in bulk amounts. The recognition of microbial biotransformation as important manufacturing tool has increased in chemical and pharmaceutical industries. In recent years, microbial transformation is increasing significantly from limited interest into highly active area in green chemistry including preparation of pharmaceutical products. This is the first review published on the usage of microbial biocatalysts for some natural product classes and natural product drugs.
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