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Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
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Processing speed and working memory training in multiple sclerosis: a double-blind randomized controlled pilot study.

Laura M Hancock1, Jared M Bruce, Amanda S Bruce

  • 1a Department of Psychiatry and Human Behavior , Alpert Medical School of Brown University, Rhode Island Hospital, Providence , RI , USA.

Journal of Clinical and Experimental Neuropsychology
|February 17, 2015
PubMed
Summary
This summary is machine-generated.

Computerized cognitive training may improve processing speed and attention in multiple sclerosis patients. This pilot study suggests potential benefits for cognitive functioning in individuals with this neurological condition.

Keywords:
Cognitive trainingComputer-based trainingMultiple sclerosisProcessing speedWorking memory

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Rehabilitation

Background:

  • Multiple Sclerosis (MS) frequently causes cognitive deficits, impacting processing speed and working memory in 40-65% of patients.
  • Cognitive impairments in MS can significantly affect daily functioning and quality of life.

Purpose of the Study:

  • To investigate the efficacy of computerized cognitive training in enhancing processing speed and working memory in individuals with MS.
  • To assess the impact of targeted cognitive training on specific cognitive domains affected by multiple sclerosis.

Main Methods:

  • A pilot study employing a randomized controlled trial design with an active training group and a sham training group.
  • Participants underwent six weeks of computerized cognitive training.
  • Cognitive performance was assessed before and after the intervention period.

Main Results:

  • The active cognitive training group demonstrated statistically significant improvements in processing speed and attention.
  • Trends towards significance were observed in other cognitive domains following the intervention.
  • The sham group did not show comparable improvements, suggesting a specific effect of the active training.

Conclusions:

  • Computerized cognitive training shows preliminary promise for improving specific cognitive functions in multiple sclerosis patients.
  • These findings support the potential of cognitive training as a therapeutic strategy for managing cognitive deficits in MS.
  • Further research with larger sample sizes is warranted to confirm these moderate improvements.