Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Conformations of Cyclohexane02:11

Conformations of Cyclohexane

17.5K
Cyclohexane does not exist in a planar form due to the high angle and torsional strain it would experience in the planar structure. Instead, it adopts non-planar chair and boat conformations.
The chair form is the most stable and derives its name from its resemblance to the “easy chair.” In the chair conformation, two carbon atoms are arranged out-of-plane — one above and one below, minimizing the torsional strain. In the chair form, the bond angle is very close to the ideal...
17.5K
Measurements of Strain01:27

Measurements of Strain

2.8K
Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
2.8K
Conformations of Cycloalkanes02:29

Conformations of Cycloalkanes

16.9K
Adolf von Baeyer attempted to explain the instabilities of small and large cycloalkane rings using the concept of angle strain — the strain caused by the deviation of bond angles from the ideal 109.5° tetrahedral value for sp3  hybridized carbons. However, while cyclopropane and cyclobutane are strained, as expected from their highly compressed bond angles, cyclopentane is more strained than predicted, and cyclohexane is virtually strain-free. Hence, Baeyer’s theory that...
16.9K
Molecular Shapes01:18

Molecular Shapes

63.5K
Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.
Two regions of electron density in a diatomic...
63.5K
Thermal Strain01:19

Thermal Strain

3.2K
Thermal strain is a concept that arises when we consider how temperature changes affect structures. Unlike the conventional assumption that structures remain constant under load, real-world scenarios often involve temperature fluctuations that can significantly impact these structures. Consider a homogeneous rod with a uniform cross-section resting freely on a flat horizontal surface. If the rod's temperature increases, the rod elongates. This elongation is proportional to the temperature...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-level expression of a newly characterized collagenase in Bacillus subtilis for efficient production of collagen peptides from fish scales.

Food chemistry·2026
Same author

Association of FVH/DWI mismatch with recanalization after mechanical thrombectomy in acute anterior-circulation large-vessel occlusion.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same author

DNA Assembly Templated by Chiral Nanotube Lattices: From Helix to Rings.

Journal of the American Chemical Society·2026
Same author

Butyrate remodels the immune-epigenetic-gut-lung axis: Emerging mechanisms and therapeutic perspectives in asthma.

Seminars in immunopathology·2026
Same author

An innovative determination approach for the support strength of stope roof: a case study.

Scientific reports·2025
Same author

Electrical Catalysis of Forbidden Transitions in Single-Molecule Devices.

Advanced materials (Deerfield Beach, Fla.)·2025

Related Experiment Video

Updated: Apr 17, 2026

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
08:41

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

Published on: June 13, 2025

1.5K

Binding configurations and intramolecular strain in single-molecule devices.

Habid Rascón-Ramos1, Juan Manuel Artés1, Yuanhui Li1

  • 1Department of Electrical and Computer Engineering, University of California, Davis, California 95616, USA.

Nature Materials
|February 17, 2015
PubMed
Summary

Researchers developed a new method using mechanical signals to precisely determine the configuration of single-molecule electronic devices. This technique improves agreement between theoretical predictions and experimental measurements for molecular junctions.

More Related Videos

A Novel Platform for In Vitro Cellular Stretching and Imaging
07:33

A Novel Platform for In Vitro Cellular Stretching and Imaging

Published on: March 10, 2026

162
High-resolution Imaging of Nuclear Dynamics in Live Cells under Uniaxial Tensile Strain
09:20

High-resolution Imaging of Nuclear Dynamics in Live Cells under Uniaxial Tensile Strain

Published on: June 2, 2019

8.4K

Related Experiment Videos

Last Updated: Apr 17, 2026

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
08:41

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

Published on: June 13, 2025

1.5K
A Novel Platform for In Vitro Cellular Stretching and Imaging
07:33

A Novel Platform for In Vitro Cellular Stretching and Imaging

Published on: March 10, 2026

162
High-resolution Imaging of Nuclear Dynamics in Live Cells under Uniaxial Tensile Strain
09:20

High-resolution Imaging of Nuclear Dynamics in Live Cells under Uniaxial Tensile Strain

Published on: June 2, 2019

8.4K

Area of Science:

  • Molecular electronics
  • Nanoscale devices
  • Quantum transport

Background:

  • Significant advancements in single-molecule electronic devices like transistors and wires have been achieved.
  • Discrepancies persist between theoretical conductance predictions and experimental measurements for molecular junctions.
  • Experimental determination of contact geometry and binding configuration in molecular junctions remains challenging.

Purpose of the Study:

  • To develop a method for characterizing the binding and contact configurations of single-molecule junctions.
  • To investigate the distribution of applied strain within molecular junctions.
  • To improve the agreement between theoretical models and experimental data in molecular electronics.

Main Methods:

  • Application of a small-amplitude, high-frequency sinusoidal mechanical signal to single-molecule devices.
  • Measurement of the current response at the applied signal frequency during junction formation and breakdown.
  • Real-time analysis of molecular junction configurations at room temperature in solution.

Main Results:

  • The method successfully determined the most probable binding and contact configurations for molecular junctions.
  • Information on strain distribution within the molecular junction was obtained.
  • Experimental results showed excellent agreement with previous theoretical model predictions.

Conclusions:

  • The mechanical modulation technique provides crucial insights into the complex configurations of single-molecule devices.
  • This approach offers a pathway to resolve discrepancies between theoretical and experimental conductance values.
  • The findings enhance the understanding and design of future molecular electronic components.