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Updated: Apr 17, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Ventilator-associated events prevention, learning lessons from the past: A systematic review
Jad Chahoud, Adele Semaan1, Khalid F Almoosa2
1Department of Management, Policy and Community Health, School of Public Health, University of Texas Health Science Center, Houston, TX, USA.
Preventing ventilator-associated events (VAE) requires updated surveillance. Expanding strategies beyond ventilator-associated pneumonia (VAP) prevention bundles improves patient outcomes.
Area of Science:
- Critical Care Medicine
- Infectious Disease Prevention
- Healthcare Surveillance Systems
Background:
- Ventilator-associated events (VAE) prevention remains a significant clinical challenge.
- Solely monitoring ventilator-associated pneumonia (VAP) is insufficient for optimal patient outcomes.
- Updated surveillance definitions advocating for the broader VAE were introduced.
Purpose of the Study:
- To review scientific efforts evaluating VAP preventive bundles.
- To analyze the recent transition to VAE surveillance methods.
- To highlight the advantages and limitations of the VAE surveillance algorithm.
Main Methods:
- Systematic review of clinical studies on VAP prevention bundles.
- Comprehensive literature review of the VAE surveillance algorithm.
- Analysis of VAE surveillance algorithm's strengths and weaknesses.
Main Results:
- VAP prevention bundles have demonstrated historical efficacy.
- The VAE definition refines and objectivizes surveillance.
- Randomized controlled trials are crucial for assessing VAE prevention impact.
Conclusions:
- Transitioning to VAE prevention bundles is recommended.
- Expanding strategies beyond VAP is necessary for improved patient outcomes.
- Further research via randomized controlled trials is vital for VAE prevention efficacy.
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