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Racial-ethnic disparities in management and outcomes among children with type 1 diabetes
Steven M Willi1, Kellee M Miller2, Linda A DiMeglio3
1Children's Hospital of Philadelphia, Philadelphia, Pennsylvania;
Insights
Racial disparities persist in pediatric type 1 diabetes care, with Black children experiencing worse outcomes and less insulin pump use than White or Hispanic children, even after accounting for socioeconomic status.
Area of Science:
- Pediatric Endocrinology
- Diabetes Research
- Health Disparities
Background:
- Previous research indicates racial/ethnic disparities in diabetes treatments and outcomes.
- It remains debated whether these disparities stem from socioeconomic status (SES) or other factors.
Purpose of the Study:
- To examine racial/ethnic disparities in therapeutic modalities and diabetes outcomes.
- Focus on pediatric participants in the T1D Exchange Clinic Registry.
Main Methods:
- Analyzed data from 10,704 pediatric participants (<18 years) with type 1 diabetes.
- Compared diabetes management and outcomes among non-Hispanic white, non-Hispanic black, and Hispanic participants.
- Adjusted for gender, age, diabetes duration, and socioeconomic status.
Main Results:
- Insulin pump use was significantly lower in Black (26%) and Hispanic (39%) children compared to White children (61%), even after SES adjustment.
- Black children had higher mean hemoglobin A1c (9.6%) and experienced more diabetic ketoacidosis and severe hypoglycemia than White (8.4%) or Hispanic (8.7%) children.
- No significant differences in outcomes were found between White and Hispanic participants after SES adjustment.
Conclusions:
- Significant disparities in insulin treatment and outcomes persist between Black children and White/Hispanic children, independent of SES.
- Further research is needed to identify barriers to insulin pump use and optimal glycemic control beyond SES in all ethnic groups.
Background And Objectives:
Previous research has documented racial/ethnic disparities in diabetes treatments and outcomes. It remains controversial whether these disparities result from differences in socioeconomic status (SES) or other factors. We examined racial/ethnic disparities in therapeutic modalities and diabetes outcomes among the large number of pediatric participants in the T1D Exchange Clinic Registry.
Methods:
The cohort included 10 704 participants aged <18 years with type 1 diabetes for ≥1 year (48% female; mean age: 11.9 ± 3.6 years; diabetes duration: 5.2 ± 3.5 years). Diabetes management and clinical outcomes were compared among 8841 non-Hispanic white (white) (83%), 697 non-Hispanic black (black) (7%), and 1166 Hispanic (11%) participants. The population included 214 high-income black and Hispanic families.
Results:
Insulin pump use was higher in white participants than in black or Hispanic participants (61% vs 26% and 39%, respectively) after adjusting for gender, age, diabetes duration, and SES (P < .001). Mean hemoglobin A1c was higher (adjusted P < .001) in black participants than in white or Hispanic participants (9.6%, 8.4%, and 8.7%). More black participants experienced diabetic ketoacidosis and severe hypoglycemic events in the previous year than white or Hispanic participants (both, P < .001). There were no significant differences in hemoglobin A1c, diabetic ketoacidosis, or severe hypoglycemia between white and Hispanic participants after adjustment for SES.
Conclusions:
Even after SES adjustment, marked disparities in insulin treatment method and treatment outcomes existed between black versus Hispanic and white children within this large pediatric cohort. Barriers to insulin pump use and optimal glycemic control beyond SES should be explored in all ethnic groups.
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