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Updated: Apr 17, 2026
Exploring the Application of Surface-enhanced Raman Scattering-based Biosensing of Individual sEVs in Disease Diagnosis and Therapeutics
Published on: March 13, 2026
An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high
Jing Wang1, Mengting Cheng, Zhen Zhang
1State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. qianliu@rcees.ac.cn.
Abstract:
Graphene oxide nanoribbons (GONRs) were covalently functionalized with an antibody using polyethylene glycol (PEG) as a linker to produce a novel probe for surface enhanced laser desorption/ionization mass spectrometry (SELDI MS). This probe provides a highly sensitive and selective platform for enrichment and MS detection of small molecules in complex media.
