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Enhancing Induced Pluripotent Stem Cell Generation by MicroRNA.

Jason Dang1, Tariq M Rana2

  • 1Department of Bioengineering, Department of Pediatrics, University of California San Diego School of Medicine, 9500 Gilman Drive MC 0762, La Jolla, CA, 92093, USA.

Methods in Molecular Biology (Clifton, N.J.)
|February 18, 2015
PubMed
Summary

This study introduces a microRNA mimic to improve somatic reprogramming for generating induced pluripotent stem cells (iPSCs). This enhanced method streamlines iPSC induction from mouse cells for research applications.

Keywords:
DifferentiationEmbryoid bodyInduced pluripotent stem cellMicroRNAMouse embryonic fibroblastsSomatic reprogrammingTeratomaTransfection

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