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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
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Parkinson's disease and sleep/wake disturbances
Keisuke Suzuki1, Masayuki Miyamoto, Tomoyuki Miyamoto
1Department of Neurology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi, 321-0293, Japan, keisuke@dokkyomed.ac.jp.
Current Neurology and Neuroscience Reports
|February 18, 2015
Summary
Sleep disturbances are common in Parkinson's disease (PD). This review covers causes, diagnosis, and management strategies to improve patient quality of life.
Area of Science:
- Neurology
- Sleep Medicine
Background:
- Sleep disturbances are a prevalent non-motor symptom in Parkinson's disease (PD).
- These issues significantly impact patient quality of life and can stem from motor and non-motor symptoms, medication, and aging.
- Neurotransmitter system changes and brainstem pathology in PD contribute to sleep-wake cycle dysregulation.
Purpose of the Study:
- To review the current understanding of sleep disturbances in Parkinson's disease.
- To discuss the various causes and contributing factors to sleep problems in PD patients.
- To outline current management strategies for sleep disturbances in PD.
Main Methods:
- Literature review focusing on sleep disturbances in Parkinson's disease.
- Analysis of factors contributing to sleep issues, including motor and non-motor symptoms.
- Discussion of diagnostic tools and management approaches.
Main Results:
- Sleep disturbances in PD are multifactorial, involving nocturnal motor symptoms, non-motor symptoms, medication effects, and age-related changes.
- Specific conditions like sleep apnea, REM sleep behavior disorder, and restless legs syndrome require screening.
- The PD Sleep Scale-2 is a valuable tool for assessing nocturnal symptoms.
Conclusions:
- Effective management of sleep disturbances is crucial for improving the quality of life for Parkinson's disease patients.
- A comprehensive approach considering all contributing factors is necessary for successful treatment.
- Early diagnosis and intervention for sleep disorders in PD are essential.
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