Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osmolality of nonionic contrast media.

H Miklautz, K Fichte, K Wegscheider

    Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin. Erganzungsband
    |January 1, 1989
    PubMed
    Summary

    Osmolality of low osmolar contrast media (CM) varies significantly, impacting clinical use. Sodium meglumine ioxaglate demonstrated lower osmolality than nonionic agents like iopromide and iohexol.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Early detection and integrated care for adolescents and young adults with psychotic disorders: the ACCESS III study.

    Acta psychiatrica Scandinavica·2017
    Same author

    One in two cancer patients is significantly distressed: Prevalence and indicators of distress.

    Psycho-oncology·2017
    Same author

    Effectiveness of one-to-one peer support for patients with severe mental illness - a randomised controlled trial.

    European psychiatry : the journal of the Association of European Psychiatrists·2017
    Same author

    Collaborative stepped care for somatoform disorders: A pre-post-intervention study in primary care.

    Journal of psychosomatic research·2016
    Same author

    Variations of heart rate variability parameters prior to the onset of ventricular tachyarrhythmia and sinus tachycardia in ICD patients. Results from the heart rate variability analysis with automated ICDs (HAWAI) registry.

    Physiological measurement·2015
    Same author

    Target organ damage and control of cardiovascular risk factors in hypertensive patients. Evidence from the multicenter ESTher registry.

    Herz·2015

    Area of Science:

    • Radiology and Medical Imaging
    • Pharmaceutical Sciences

    Background:

    • Low osmolar contrast media (CM) are crucial in medical imaging.
    • Despite similar iodine concentrations, CM exhibit clinically relevant osmolality differences.

    Purpose of the Study:

    • To precisely measure and compare the osmolality of commercially available low osmolar contrast media.
    • To identify osmolality variations among different CM formulations.

    Main Methods:

    • Vapor pressure method was employed for osmolality measurement.
    • Five batches each of iopamidol, iohexol, iopromide, and sodium meglumine ioxaglate were analyzed.

    Main Results:

    • Sodium meglumine ioxaglate exhibited lower osmolality compared to nonionic CM at equal iodine concentrations.
    • Iopromide showed the lowest osmolality among nonionic agents, while iohexol had the highest.
    • Observed differences in osmolality were statistically significant.

    Conclusions:

    • Osmolality varies significantly among low osmolar contrast media, influencing their clinical application.
    • Differences are attributed to molecular association and hydration variations within CM solutions.

    Related Experiment Videos