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Cost-effectiveness study of pediatric atopic dermatitis in Asia: atopiclair vs. regular emollient (AD-ATOP)

Mark B Y Tang, Kin Fon Leong, Liang-Shiou Ou

    Journal of Drugs in Dermatology : JDD
    |February 18, 2015
    PubMed

    Insights

    Atopiclair, a non-steroidal cream, is a cost-effective treatment for childhood atopic dermatitis (AD) compared to regular emollients. It offers significant annual cost savings across high, middle, and low-income Asia-Pacific countries.

    Area of Science:

    • Dermatology
    • Health Economics
    • Pediatrics

    Background:

    • Atopic dermatitis (AD) is a common childhood condition impacting quality of life.
    • Current AD management relies on proactive moisturizing treatments.

    Purpose of the Study:

    • To evaluate the cost-effectiveness of Atopiclair versus regular emollient for pediatric mild-to-moderate AD.
    • Study focused on 12 Asia-Pacific countries.

    Main Methods:

    • A Markov decision model was utilized for cost-effectiveness analysis.
    • Data sourced from literature review, expert opinion, fee schedules, and a 2012 survey.
    • Analysis adopted a societal perspective.

    Main Results:

    • Atopiclair demonstrated cost-effectiveness against regular emollient.
    • Annual cost savings per patient were USD786 (high-income), USD499 (middle-income), and USD289 (low-income).
    • Sensitivity analyses confirmed Atopiclair's cost-effectiveness.

    Conclusions:

    • Modeling indicates Atopiclair is a cost-effective option for managing pediatric mild-to-moderate AD.
    • This finding applies to the studied Asia-Pacific nations.
    Abstract

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