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Can we diagnose isolated, exercise-induced heart failure with normal ejection fraction?
Jaroslav Meluzin1,2, Zdenka Gregorova1,2, Monika Spinarova1,2
1Department of Cardiovascular Diseases, St. Anne´s University Hospital, ICRC, Brno, Czech Republic.
Diagnosing exercise-induced heart failure with normal ejection fraction (HFNEF) is challenging due to limited data. Further research is needed to establish reliable diagnostic methods for this common condition.
Area of Science:
- Cardiology
- Heart Failure Research
Background:
- Exertional dyspnea often necessitates exercise testing for diagnosing heart failure with normal ejection fraction (HFNEF).
- HFNEF presents a significant clinical challenge due to diagnostic complexities.
Purpose of the Study:
- To review current data on the prevalence, clinical significance, and diagnostic establishment of isolated, exercise-induced HFNEF.
- To highlight the limitations and conflicts in diagnosing exercise-induced HFNEF.
Main Methods:
- Literature review evaluating existing data on exercise-induced HFNEF.
- Analysis of diagnostic criteria, focusing on left ventricular filling pressure (LVFP) elevation during exercise.
Main Results:
- Despite clinical importance, data on diagnosing exercise-induced HFNEF are limited and conflicting.
- Current diagnostic reliance on exercise-induced LVFP elevation lacks consensus regarding prediction by echocardiography.
- Invasive LVFP measurements also face challenges in defining normal values.
Conclusions:
- Significant diagnostic challenges and conflicting results exist for exercise HFNEF.
- New diagnostic approaches are required for reliable diagnosis of exercise HFNEF.
- Further research is encouraged in this clinically vital area of heart failure.
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