Related Experiment Video
Updated: Apr 17, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Coronary heart disease and risk factors in latin america
Fernando Lanas1, Pamela Serón1, Alejandra Lanas2
1Departamento de Medicina Interna, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.
Insights
Cardiovascular diseases are a major threat in Latin America, driven by prevalent risk factors like obesity and dyslipidemia. Addressing these issues is crucial for reducing heart disease mortality in the region.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Cardiovascular diseases (CVDs) are the primary cause of mortality in Latin America, with ischemic heart disease being the leading specific cause.
- Prevalence of CVD risk factors, including overweight, obesity, dyslipidemia, diabetes mellitus, and tobacco smoking, is high and exhibits regional variations.
- Increasing rates of overweight and obesity, strongly linked to sedentarism, are a significant concern, particularly noted in Mexico.
Purpose of the Study:
- To analyze the prevalence and patterns of cardiovascular disease risk factors in Latin America.
- To identify the most significant attributable risks for myocardial infarction in the region.
Main Methods:
- Utilized data from national surveys, such as the 2012 Mexican National Survey.
- Incorporated data from the INTERHEART study, which analyzed risk factors for myocardial infarction in over 27,000 subjects across 52 countries, with a focus on Latin America.
Main Results:
- Characteristic dyslipidemia includes low high-density lipoprotein cholesterol, elevated low-density lipoprotein cholesterol, and increased triglycerides.
- National prevalence rates for diabetes mellitus range from 2.8% to 9.4%, and for tobacco smoking from 12.8% to 42%.
- The INTERHEART data for Latin America identified abdominal obesity, dyslipidemia, and smoking as the most significant attributable risks for myocardial infarction.
Conclusions:
- High prevalence of modifiable risk factors like obesity, dyslipidemia, and smoking significantly contributes to the burden of cardiovascular diseases in Latin America.
- Targeted public health interventions focusing on these key risk factors are essential for mitigating cardiovascular mortality in the region.
Abstract:
Cardiovascular diseases are the leading cause of death in Latin America, with ischemic heart disease as the principal cause in most countries. Risk factors for cardiovascular disease are highly prevalent in the region, but there are international variations in the pattern and level of risk factors. Overweight and obesity are increasing. In the 2012 Mexican National Survey, overweight or obesity was found in 64.9% of men and 73% of women, and they were strongly associated with sedentarism. The most characteristic dyslipidemia abnormality in the region is low high-density lipoprotein cholesterol, followed by elevated low-density lipoprotein cholesterol and increased levels of triglycerides. National diabetes mellitus prevalence ranges from 2.8% to 9.4% and tobacco smoking from 12.8% to 42%. According to the INTERHEART (A Study of Risk Factors for First Myocardial Infarction in 52 Countries and Over 27,000 Subjects) data for Latin America, the highest attributable risks for myocardial infarction were related to abdominal obesity, dyslipidemia, and smoking.
Related Concept Videos
Coronary Artery Disease I: Introduction
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease III: Clinical Manifestations
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
