Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Seizures: Classification

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

Antiepileptic Drugs: Sodium Channel Blockers

Antiepileptic Drugs: Sodium Channel Blockers

Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...

Antiepileptic Drugs: GABAergic Pathway Potentiators

Antiepileptic Drugs: GABAergic Pathway Potentiators

γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...

Antiepileptic Drugs: Glutamate Antagonists

Antiepileptic Drugs: Glutamate Antagonists

Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

American Heart Association/American Stroke Association 2026 Guideline for the Early Management of Patients with Acute Ischemic Stroke: Pediatric Perspective.

Indian pediatrics·2026

Same author

Parental autistic traits and neurodevelopmental outcomes in children with autism spectrum disorder: a family phenotype perspective.

Developmental neurorehabilitation·2026

Same author

Behavioral Adverse Effects of Levetiracetam: Pragmatic Research vs Research in Highly Controlled Idealized Settings.

Indian pediatrics·2026

Same author

Behavioral Adverse Effects During Initial Six Weeks of Levetiracetam Therapy in Children with Epilepsy: A Prospective Cohort Study.

Indian pediatrics·2026

Same author

Bronchiolitis Obliterans as an Initial Presentation in an Adolescent With HIV: A Case Report.

Pediatric pulmonology·2026

Same author

When Content Overwhelms Capability: Time to Think Modular!

Indian pediatrics·2026

Same journal

Adding Purpose to Pulse: 2025 Pediatric Life Support Update.

Indian pediatrics·2026

Same journal

PEX6-Associated Heimler Syndrome 2 Presenting with Bernard-Soulier Syndrome.

Indian pediatrics·2026

Same journal

HLA Typing in Pediatric Celiac Disease: From Genetic Association to Clinical Application.

Indian pediatrics·2026

Same journal

Microbial Conversations Between the Gut and Urinary Tract: Emerging Implications for Kidney and Urinary Tract Diseases.

Indian pediatrics·2026

Same journal

Prevalence and Associated Social Factors of Prediabetes in Children and Adolescents in India: A Systematic Review and Meta-Analysis.

Indian pediatrics·2026

Same journal

Comparison of Early Intrapleural Fibrinolytic Therapy, Versus Administration After Failure of Intercostal Drainage in Children with Empyema Thoracis: A Systematic Review.

Indian pediatrics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 17, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

Benign infantile seizures.

Devendra Mishra¹, Niraj Kumar Nikunj, Monica Juneja

¹Departments of Pediatrics, Lok Nayak Hospital and *Chacha Nehru Bal Chikitsalaya, Maulana Azad Medical College, Delhi, India. Correspondence to: Dr Devendra Mishra, Department of Pediatrics, Maulana Azad Medical College and associated Lok Nayak Hospital, Delhi 110 002, India. drdmishra@gmail.com.

Indian Pediatrics

|February 19, 2015

Summary

This summary is machine-generated.

Benign infantile seizures, a rare idiopathic epilepsy, present as focal seizure clusters in infants. These cases showed no recurrence, indicating a favorable prognosis.

More Related Videos

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Continuous Video Electroencephalogram during Hypoxia-Ischemia in Neonatal Mice

Continuous Video Electroencephalogram during Hypoxia-Ischemia in Neonatal Mice

Published on: June 11, 2020

Related Experiment Videos

Last Updated: Apr 17, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Continuous Video Electroencephalogram during Hypoxia-Ischemia in Neonatal Mice

Continuous Video Electroencephalogram during Hypoxia-Ischemia in Neonatal Mice

Published on: June 11, 2020

Area of Science:

Pediatric Neurology
Epileptology

Background:

Benign infantile seizures are an uncommon yet significant form of idiopathic epilepsy in infants.
This study addresses the infrequent reporting of this specific seizure type.

Observation:

Four cases of benign infantile seizures were identified within a 9-month period.
All infants presented with clusters of focal seizures.
Key characteristics included normal developmental milestones and unremarkable hematological and biochemical assessments.

Findings:

A significant finding was the absence of seizure recurrence in all cases during a follow-up period of 5 to 9 months.
This suggests a self-limiting or highly manageable course for this specific seizure presentation.

Implications:

Early identification of this benign infantile seizure syndrome is crucial.
Accurate diagnosis has significant implications for appropriate therapeutic strategies and accurate prognostic counseling for affected families.