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Reversible changes in diffusion- and perfusion-based imaging in cerebral venous sinus thrombosis

Ning Lin1, Andrew K Wong1, Lindsay J Lipinski1

  • 1Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, USA Department of Neurosurgery, Gates Vascular Institute at Kaleida Health, Buffalo, New York, USA.

Journal of Neurointerventional Surgery
|February 19, 2015
PubMed

Insights

Diffusion and perfusion imaging can predict outcomes in cerebral venous sinus thrombosis (CVST) stroke. Abnormal imaging findings in a CVST patient largely reversed after endovascular treatment, suggesting its prognostic value.

Area of Science:

  • Neurology
  • Radiology
  • Vascular Imaging

Background:

  • Diffusion- and perfusion-based imaging are standard for ischemic stroke assessment.
  • Cerebral venous sinus thrombosis (CVST) is an uncommon stroke cause, typically managed with anticoagulation.
  • The prognostic utility of advanced imaging in CVST remains unclear.

Observation:

  • A patient with CVST presented with abnormal diffusion and perfusion MRI/CT findings.
  • The patient underwent endovascular treatment due to failed medical therapy.

Findings:

  • Post-treatment imaging revealed significant reversal of the initial diffusion and perfusion abnormalities.
  • This suggests a positive response to endovascular intervention.

Implications:

  • Diffusion- and perfusion-based imaging may hold prognostic value in CVST cases.
  • Endovascular treatment could lead to favorable imaging outcomes in select CVST patients.
  • Further research is warranted to establish imaging's role in guiding CVST management.

Keywords:
CT perfusionMRIStrokeVein

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