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Intestinal stricture in Crohn's disease.
Chen-Wang Chang1, Jau-Min Wong2, Chien-Chih Tung3
1Department of Gastroenterology, Mackay Memorial Hospital, Taipei; Mackay Junior College of Medicine, Nursing and Management, Taipei; Mackay Medical College, New Taipei, Taiwan.
Intestinal Research
|February 19, 2015
Summary
Crohn
Area of Science:
- Gastroenterology and Clinical Medicine
Background:
- Crohn's disease (CD) is a chronic inflammatory condition affecting the gastrointestinal tract with increasing incidence in Asia.
- Intestinal complications, particularly strictures, affect a significant proportion of CD patients, often necessitating surgical intervention.
- Early diagnosis and management are crucial for preventing disability and mortality in Crohn's disease patients with strictures.
Purpose of the Study:
- To review the current incidence of Crohn's disease (CD) with intestinal strictures.
- To explore the etiology and risk factors associated with stricture formation in CD.
- To summarize current diagnostic and management strategies for strictures in Crohn's disease.
Main Methods:
- Literature review of studies on Crohn's disease incidence, etiology, diagnosis, and management of strictures.
- Analysis of data regarding the prevalence of small bowel and colonic strictures in CD patients.
- Synthesis of information on diagnostic modalities and therapeutic approaches for CD-related strictures.
Main Results:
- The incidence and prevalence of Crohn's disease are rising, especially in Asian populations.
- Small bowel strictures occur in 25% and colonic strictures in 10% of CD patients, leading to complications.
- A substantial number of CD patients require surgery due to strictures and other complications.
Conclusions:
- Strictures are a common and serious complication of Crohn's disease, significantly impacting patient outcomes.
- Understanding the incidence, etiology, and effective management of CD-related strictures is vital.
- Timely diagnosis and appropriate interventions can mitigate the long-term morbidity associated with Crohn's disease strictures.
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