Evolving clonal nevus-case report with serial digital dermatoscopy and dermatopathology.

Area of Science:

• Dermatology
• Dermatopathology

Background:

• Melanocytic nevi can undergo changes over time.
• Clonal nevi are a specific subtype of melanocytic nevi.
• The evolution of melanocytic nevi is of clinical interest.

Purpose of the Study:

• To document and present a case of a clonal nevus evolving from a benign melanocytic nevus.
• To provide clinical, dermatoscopic, and dermatopathologic images of this evolution.
• To highlight the novelty of this documented evolutionary process in the literature.

Main Methods:

• Case presentation from a primary care skin cancer practice.
• Clinical and dermatoscopic imaging.
• Dermatopathologic examination.
• Literature search for similar documented cases.

Main Results:

• A clonal nevus was observed to arise from a previously banal melanocytic nevus.
• The evolution occurred over a 15-month period.
• Clinical, dermatoscopic, and dermatopathologic images were obtained.
• No prior published dermatoscopy images of an evolving clonal nevus were found.

Conclusions:

• This case illustrates the potential for benign melanocytic nevi to evolve into clonal nevi.
• The documentation provides valuable visual resources for clinicians and researchers.
• This represents the first reported case with dermatoscopic images of an evolving clonal nevus.