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Updated: Apr 17, 2026
Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
Portal flow modulation in auxiliary partial orthotopic liver transplantation
Mohamed Rela1, Anand Bharathan, Kumar Palaniappan
1Institute of Liver Disease & Transplantation, Global Hospital & Health City, National Foundation for Liver Research, Chennai, Tamil Nadu, India; Institute of Liver Studies, Kings College Hospital, Denmark Hill, London, UK.
Abstract:
APOLT is a suitable technique of liver transplantation in patients with ALF and some types of MLD. Portal venous steal is a problem with this procedure that leads to graft dysfunction and failure. Modulation of the portal flow to the graft and native liver can help in preventing this problem. We discuss the pathophysiology of this complication, review available literature regarding its management, and describe our results using the technique of graded hemiportal banding to achieve adequate perfusion for the graft and native liver.
