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Interictal regional delta slowing in cerebral sinus vein thrombosis

Sharon Aharoni1, Hadassa Goldberg-Stern, Liora Kornreich

  • 1Departments of *Neurology ‡Imaging, Schneider Children's Medical Center of Israel, Petach Tikva †Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The Neurologist
|February 19, 2015
PubMed

Insights

Focal delta activity on electroencephalography may indicate brain abnormalities. In a child with seizures, this EEG finding helped detect cerebral sinus vein thrombosis missed by initial CT scans.

Area of Science:

  • Neurology
  • Neurophysiology
  • Pediatric Neurology

Background:

  • Regional delta activity on electroencephalography (EEG) suggests potential structural brain abnormalities.
  • Cerebral sinus vein thrombosis (CSVT) is a rare but serious condition that can present with diverse neurological symptoms.

Observation:

  • A 5-year-old boy experienced severe headache and focal seizures with a normal neurological exam and CT scan.
  • Initial EEG revealed focal delta activity, prompting further investigation.

Findings:

  • Emergent MRI identified thrombosis of the left sigmoid sinus and jugular vein.
  • No parenchymal brain lesions were detected, highlighting the sensitivity of EEG.

Implications:

  • Regional delta activity may serve as an early marker for brain tissue damage in CSVT.
  • EEG findings can provide crucial information complementing neuroimaging in diagnosing CSVT.

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