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Updated: Apr 17, 2026

Isolation of Atrial Myocytes from Adult Mice
Published on: July 25, 2019
[Do natriuretic peptides have a new chance in treatment of heart failure?]
Abstract:
The effect of natriuretic peptides on cardiovascular and renal system offers a potential benefit in therapy of hypertension and heart failure; however the current results of clinical trials are not encouraging. Synthetic B natriuretic peptide has demonstrated short-term hemodynamic improvement in patients, but in terms of renal function and long-term prognosis the effect was questionable. Nevertheless, new hope is ularitid a dual inhibitor of neprilysin and ARB: LCZ 696, the ongoing clinical studies and previous data from pilot studies appear promising.
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