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Patient compliance with postnatal thromboprophylaxis: An observational study.
C E Hordern1, C W Bircher1, E C Prosser-Snelling1
1a Department of Obstetrics and Gynaecology , Norfolk and Norwich University Hospital NHS Foundation Trust , Norwich , UK.
Summary
Postnatal thromboprophylaxis compliance is high, with 83% of women completing their low-molecular-weight heparin course. Most women self-injected, but many desired more information for future pregnancies.
Area of Science:
- Obstetrics and Gynecology
- Pharmacology
- Public Health
Background:
- Postnatal thromboprophylaxis use has increased following updated clinical guidelines.
- Ensuring adherence to prescribed anticoagulant therapy is crucial for preventing postpartum venous thromboembolism.
- Understanding patient experiences and barriers is key to optimizing treatment protocols.
Purpose of the Study:
- To assess compliance rates with prescribed low-molecular-weight heparin (LMWH) for postnatal thromboprophylaxis.
- To identify barriers encountered by women in completing their full course of LMWH therapy.
- To evaluate women's willingness to undertake thromboprophylaxis in future pregnancies.
Main Methods:
- Prospective study involving postnatal women meeting thromboprophylaxis criteria.
- Telephone follow-up at 14 days postpartum to collect data on compliance and experiences.
- Data collection on self-injection versus reliance on family members for administration.
Main Results:
- High reported compliance with the full course of postnatal thromboprophylaxis (83%).
- Majority of women administered LMWH themselves (54%), with a substantial proportion relying on family (39%).
- Over 94% of women expressed willingness to use thromboprophylaxis in future pregnancies, though some requested more information.
Conclusions:
- Reported compliance with postnatal thromboprophylaxis is notably high.
- Factors contributing to compliance include maternal motivation, adequate information provision, and accessible healthcare support.
- Further research into patient education and support systems may enhance adherence and patient satisfaction.
