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Updated: Apr 17, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
Insights
Tachycardia-induced cardiomyopathy (TIC) is a reversible heart condition caused by prolonged rapid heart rate. Early detection and treatment, including heart rate normalization, are crucial for recovery of heart function.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Cardiomyopathy encompasses diverse heart muscle diseases impairing cardiac function.
- Tachycardia-induced cardiomyopathy (TIC) results from sustained rapid heart rate, causing heart dilation and systolic dysfunction.
- Clinical presentation of TIC includes heart failure symptoms, but it is reversible upon heart rate normalization.
Purpose of the Study:
- To review the pathophysiology, diagnosis, and treatment of tachycardia-induced cardiomyopathy.
- To highlight the importance of identifying and managing arrhythmias that can lead to reversible heart dysfunction.
Main Methods:
- Literature review of studies on tachycardia-induced cardiomyopathy.
- Analysis of common arrhythmias associated with TIC, including atrial fibrillation, atrial flutter, supraventricular tachycardia, ventricular tachycardia, and ventricular extrasystoles.
- Discussion of diagnostic approaches, often retrospective after heart rate normalization and left ventricular function recovery.
Main Results:
- Sustained tachycardia can lead to significant left ventricular dysfunction and heart failure.
- Atrial fibrillation, atrial flutter, supraventricular tachycardia, ventricular tachycardia, and frequent ventricular extrasystoles are common causes of TIC.
- Diagnosis is typically made after heart rate control and observed recovery of left ventricular function.
Conclusions:
- Tachycardia-induced cardiomyopathy is a potentially reversible cause of heart failure.
- Prompt recognition and management of the underlying arrhythmia are essential for successful treatment and improved cardiac function.
- Despite over a century since its first description, understanding of TIC's precise mechanisms remains limited, necessitating further research.
Abstract:
Cardiomyopathy is a heterogeneous group of diseases of heart muscle accompanied with impaired cardiac function. Tachycardia-induced cardiomyopathy (TIC) is caused by prolonged tachycardia leading to dilatation and systolic dysfunction with clinical manifestation of heart failure. This state is reversible after normalization of heart rate. The diagnosis is usually made retrospectively after normalization of heart rate and recovery of left ventricular function (LVF). More than 100 years after the first documented case (described in 1913 in a young patient with atrial fibrillation and symptoms of heart failure [25]) is still limited knowledge of pathophysiological mechanisms. The most common arrhythmias responsible for the TIC include atrial fibrillation [1,2], atrial flutter [3], incessant supraventricular tachycardia [4], ventricular tachycardia (VT) [5] and frequent ventricular extrasystoles (VES) [6]. TIC detection and therapeutic intervention is crucial considering potential reversibility of tachycardia. Current options of treatment involve drug therapy and surgical or catheter ablation.
Related Concept Videos
Cardiomyopathy I: Introduction and Classification
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
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