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Updated: Apr 17, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Sinonasal melanoma arising from conjunctival primary acquired melanosis
Mark Shehata1, Dan Gombos2, John Bishop3
1University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Abstract:
A 66-year-old woman was treated with excision and cryotherapy for recurrent primary acquired melanosis (PAM) with atypia of the right conjunctiva. Four years later, she developed a melanoma of the ipsilateral inferior turbinate and nasolacrimal duct. She was treated with right medial maxillectomy and postoperative radiation therapy. This is the first reported case of conjunctival PAM resulting in delayed progression to melanoma in the nasolacrimal duct and sinonasal cavity.
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