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Updated: Apr 17, 2026
Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
Pulsatile motion of trabecular meshwork in a patient with iris cyst by phase-sensitive optical coherence tomography:
Yi-Chen Sun1, Peng Li1, Murray Johnstone1
11 Department of Ophthalmology, Buddhist Tzu Chi General Hospital, Taipei Branch, New Taipei City, Taiwan ; 2 Department of Ophthalmology, 3 Department of Bioengineering, University of Washington, Seattle, WA 98104, USA.
Abstract:
A 45-year-old man was diagnosed with a 3 mm × 3 mm iris cyst located at 9 o'clock behind iris and protruding into temporal angle by slit lamp examination, gonioscopy, and ultrasound biomicroscopy (UBM). Phase-sensitive optical coherence tomography (PhS-OCT) was applied on this case for the quantitative measurements of trabecular meshwork (TM) motion. The frequency of TM motion was with the same rhythm of the patient's peripheral pulse. Its amplitude on the closed angle region showed significant smaller than the open angle region. PhS-OCT can be a useful tool for the diagnosis and follow-up in ocular diseases surrounding iridocorneal angle.
