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L-ascorbic acid produces hypoglycaemia and hyperinsulinaemia in anaesthetized rats
J T Cheng1, S C Hsieh-Chen, C L Tsai
1Department of Pharmacology, College of Medicine, National Cheng Kung University, Taiwan, Republic of China.
The Journal of Pharmacy and Pharmacology
|May 1, 1989
Abstract:
L-Ascorbic acid (Vitamin C) produced a marked reduction in the blood glucose concentration following intravenous injection (20-100 mg kg-1) to anaesthetized rats. This hypoglycaemic effect was accompanied by an increase in plasma insulin concentration. D-ascorbic acid produced a similar hypoglycaemic effect.