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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis I01:29

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Related Experiment Video

Updated: Apr 17, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Noninvasive test for tuberculosis detection among primates.

Tiffany M Wolf, Lawrence Mugisha, Fernanda Miyagaki Shoyama

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    |February 20, 2015
    PubMed
    Summary

    A new fecal PCR test accurately detects tuberculosis in primates. This noninvasive method aids epidemiologic studies of Mycobacterium tuberculosis in wildlife and captive populations.

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    Area of Science:

    • Veterinary Medicine
    • Primate Health
    • Infectious Diseases

    Background:

    • Epidemiologic studies of tuberculosis in primates are hindered by traditional testing limitations.
    • Noninvasive diagnostic tools are needed for wildlife and captive primate populations.

    Purpose of the Study:

    • To evaluate the utility of PCR amplification of Mycobacterium tuberculosis insertion element IS6110 from fecal samples as a noninvasive screening test for tuberculosis in primates.

    Main Methods:

    • Fecal samples were collected from primates.
    • PCR amplification targeting the IS6110 insertion element of Mycobacterium tuberculosis was performed.

    Main Results:

    • The fecal PCR test successfully detected active tuberculosis in inoculated macaques.
    • The test also identified tuberculosis in naturally exposed chimpanzees.

    Conclusions:

    • PCR amplification of IS6110 from fecal samples is a valuable noninvasive tool for diagnosing tuberculosis in primates.
    • This method can enhance epidemiologic surveillance of tuberculosis in diverse primate populations.