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S-methylation in motorneuron disease and Parkinson's disease
R H Waring1, G B Steventon, S G Sturman
1Department of Biochemistry, University of Birmingham.
Lancet (London, England)
|August 12, 1989
Abstract:
Thiolmethyltransferase activity has been measured in newly diagnosed, untreated patients with idiopathic Parkinson's disease and motorneuron disease, and in normal volunteers. In Parkinsonian patients, mean thiolmethyltransferase activity was low (300 U/mg protein [SD 96]) compared with that in controls (947 [409]), whereas activity was high in patients with motorneuron disease (2077 [825]).