Prevalence of coronary atherosclerosis in patients with aortic valve replacement

Insights

Preoperative coronary angiography remains crucial for patients undergoing aortic valve replacement, as coronary artery disease prevalence is high and has not significantly changed over a decade. This ensures optimal patient care and surgical planning.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Diagnostic Imaging

Background:

  • Coronary artery disease (CAD) is common in patients with aortic valve disease, necessitating preoperative coronary angiography before aortic valve replacement (AVR).
  • Despite declining CAD mortality in the general population, the necessity of routine preoperative angiography for all AVR patients remains uncertain.

Purpose of the Study:

  • To determine the prevalence of angiographically defined CAD in patients undergoing AVR.
  • To analyze trends in CAD prevalence over a ten-year period (1988-1998) in this patient cohort.

Main Methods:

  • Retrospective cross-sectional study of 1181 patients undergoing AVR between 1988 and 1998.
  • Exclusion of patients with prior CAD history or younger than 25 years.
  • Definition of coronary atherosclerosis as ≥50% stenosis in one or more coronary arteries via preoperative angiography.

Main Results:

  • Coronary atherosclerosis was detected in 40% of patients (472/1181) on preoperative angiography.
  • Prevalence of CAD varied annually between 30% and 50% but showed no significant trend over the study period.
  • Known ischemic heart disease risk factors were associated with the presence of CAD.

Conclusions:

  • The prevalence of angiographically confirmed CAD in patients awaiting AVR remains high.
  • No significant temporal change in CAD prevalence was observed between 1988 and 1998.
  • Preoperative coronary angiography is recommended for all patients prior to AVR due to the persistent high prevalence of CAD.
Abstract

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
562
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
1.0K
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.4K
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
821
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
559
Aortic Regurgitation IV: Nursing Management01:17

Aortic Regurgitation IV: Nursing Management

A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
416