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Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
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Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
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Articles linked to this work by shared authors, journal, and citation graph.

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Drug-eluting stents for all patients.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2015
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New drug-eluting stents, optimizing technique, and the problem of drug-eluting stent restenosis.

Minerva cardioangiologica·2005
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Methodological considerations and approach to cross-technique comparisons using in vivo coronary plaque characterization based on intravascular ultrasound radiofrequency data analysis: insights from the Integrated Biomarker and Imaging Study (IBIS).

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One year clinical follow up of paclitaxel eluting stents for acute myocardial infarction compared with sirolimus eluting stents.

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How to accelerate the endothelialization of stents.

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Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
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Wake up call for Dutch cardiologists.

P W Serruys, A T L Ong

    Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
    |February 20, 2015
    PubMed
    Summary

    Drug-eluting stents significantly reduce restenosis in both high- and low-risk patients. These advanced stents are cost-effective, challenging perceptions of higher expense and limited benefit.

    Area of Science:

    • Cardiovascular Medicine
    • Interventional Cardiology
    • Health Economics

    Background:

    • Drug-eluting stents (DES) offer reduced restenosis rates compared to bare metal stents.
    • Despite proven benefits, DES market penetration in the Netherlands remains low (15-25%) since 2002.
    • Perceived high cost and limited applicability to high-risk patients hinder DES adoption.

    Purpose of the Study:

    • To evaluate the cost-effectiveness and clinical benefits of drug-eluting stents across patient risk subgroups.
    • To address misconceptions regarding the value and applicability of DES in interventional cardiology.
    • To advocate for broader insurance coverage of DES for Dutch patients.

    Main Methods:

    • Analysis of randomized trial data comparing DES and bare metal stents.
    Keywords:
    cost-effectiveness analysisdrug-eluting stents

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  • Economic evaluation of DES implementation from individual and societal perspectives.
  • Review of market penetration data and perceived barriers to adoption.

    • Main Results:

    • Drug-eluting stents demonstrate significant benefits in reducing restenosis for both high-risk and low-risk patient subgroups.
    • The cost-effectiveness analysis supports the use of DES on both individual and societal levels.
    • Current market penetration does not reflect the proven clinical and economic advantages of DES.

    Conclusions:

    • Drug-eluting stents provide substantial clinical benefits and are cost-effective across diverse patient populations.
    • Addressing perceptions of cost and benefit is crucial for increasing DES utilization.
    • Immediate insurance recognition is recommended to ensure Dutch patients access this advanced technology.