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Quality of secondary cardiovascular prevention in specialised care in the Netherlands: the SOLID study
Insights
In the Netherlands, many cardiovascular disease patients on lipid-lowering drugs meet cholesterol targets. However, a significant number remain undertreated or untreated, indicating a need for improved secondary cardiovascular prevention strategies.
Area of Science:
- Cardiology
- Public Health
- Pharmacotherapy
Background:
- Secondary cardiovascular prevention is crucial for patients with existing cardiovascular disease (CVD).
- National guidelines recommend strict cholesterol targets for high-risk patients.
- Lipid-lowering therapy is a cornerstone of CVD management.
Purpose of the Study:
- To assess the achievement of national cholesterol targets in Dutch patients with CVD under specialized care.
- To evaluate the current lipid-lowering treatment patterns in this patient population.
Main Methods:
- A hospital-based cohort study was conducted.
- Data were collected from 7377 patients treated by 41 cardiologists and internists in the Netherlands.
- The study analyzed medication use and lipid levels against national guidelines.
Main Results:
- 41% of patients indicated for lipid-lowering therapy achieved target cholesterol levels.
- 42% received medication but remained above target cholesterol levels.
- 11% were untreated, and 5% lacked recent lipid measurements.
Conclusions:
- While treatment rates have improved compared to previous studies, optimal cholesterol management remains a challenge.
- A substantial proportion of Dutch CVD patients in specialized care are not achieving recommended cholesterol targets.
- Further optimization of lipid-lowering therapy is necessary to improve secondary cardiovascular prevention outcomes.
Objective:
To determine the extent to which Dutch patients with a history of cardiovascular disease and high cholesterol levels, treated in specialised care, are achieving low-cholesterol targets as defined by national guidelines.
Design:
Hospital-based cohort study.
Setting:
Practices of 41 hospital-based cardiologists and internists in the Netherlands.
Subjects:
7377 patients.
Results:
Forty-one percent of the patients with an indication for secondary cardiovascular prevention by lipid-lowering drug treatment were receiving medication and were achieving cholesterol targets, 42% were receiving lipid-lowering medication but had cholesterol levels above target, 11% were not receiving treatment, and 5% had no recent lipid measurements.
Conclusion:
Compared with previous studies, the SOLID study shows that a relatively large percentage of the Dutch patients under specialised care with a history of cardiovascular disease and an indication for cholesterol-reducing therapy are currently being treated. A considerable proportion of the patients, however, are still not receiving optimal treatment and more than 10% are not being treated at all.
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